What Is Palmitoylethanolamide (PEA)? A Plain-English Introduction
PEA is a naturally occurring fatty acid your body already makes to calm pain and inflammation. Here’s what it is, how it works, and what the science says.
What Is Pea
Palmitoylethanolamide vs CBD: Mechanisms, Evidence, and How to Choose
PEA and CBD both target inflammation and discomfort through distinct pathways. Learn the key differences, shared ground, and which may suit your situation.
Palmitoylethanolamide, Mast Cells, and Neuroinflammation: The Cellular Science Behind the Signal
Explore how PEA stabilizes mast cells and modulates neuroinflammatory signaling through PPAR-α activation and the ALIA mechanism. Informational, not medical adv
What ‘Endogenous’ Means for PEA—and Why It Matters for Pain and Inflammation
PEA is a fatty acid your body already makes. Understanding what ‘endogenous’ means reveals why PEA supplements work differently from most anti-inflammatories.
What Is Palmitoylethanolamide (PEA)? Benefits, Research, and Safety Explained (2026)
What palmitoylethanolamide is, how PEA is thought to work, what the research covers, the forms available, and what is known about its safety.
How Does Palmitoylethanolamide (PEA) Work? Mechanisms of Action Explained
Discover how palmitoylethanolamide (PEA) works — covering PPAR-α activation, mast cell stabilization, and neuroinflammatory signaling. Informational only.
Palmitoylethanolamide (PEA): From 1950s Egg-Yolk Discovery to Modern Pain Research
Trace the history of palmitoylethanolamide (PEA) — from its discovery in egg yolk in the 1950s to contemporary clinical trials for pain and inflammation.